ISDA: 9DW0

Deposition Date 2024-10-08

Release Date 2025-10-15

Last Version Date 2026-03-11

Entry Detail

PDB ID:

9DW0

Keywords:

STRUCTURAL PROTEIN

Title:

Human ClpX-bound ClpP

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 0.1197

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:ATP-dependent Clp protease pr
Gene (Uniprot):CLPP
Chain IDs:A (auth: H), B (auth: I), C (auth: J), D (auth: K), E (auth: L), F (auth: M), G (auth: N), H (auth: O), I (auth: P), J (auth: Q), K (auth: R), L (auth: S), M (auth: T), N (auth: U)
Chain Length:192
Number of Molecules:14
Biological Source:Homo sapiens

UniProt ID:Q16740 Pfam ID:PF00574 EC:3.4.21.92

Ligand Molecules

Primary Citation

Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation.

Chen, W, Lander, G.C, Yang, J.Show

Nat Commun 17 1064 1064 (2026)

PMID: 41593052 DOI: 10.1038/s41467-025-67010-1

Primary Citation of related structures

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