9DPI image
Deposition Date 2024-09-21
Release Date 2026-03-18
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9DPI
Keywords:
RNA BINDING PROTEIN
Title:
Cryo-EM structure of SerRS dimer in complex with two SIRT2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.90 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9DPI validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:NAD-dependent protein deacety
Gene (Uniprot):SIRT2
Chain IDs:B (auth: C), D (auth: E)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q8IXJ6 Pfam ID:PF02146 EC:2.3.1.286
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine--tRNA ligase, cytoplas
Gene (Uniprot):SARS1
Chain IDs:A (auth: D), C (auth: F)
Chain Length:0
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P49591 Pfam ID:PF02403, PF00587 EC:6.1.1.11
Ligand Molecules
AR6
Primary Citation
A metabolite-bridged complex between SerRS and SIRT2 couples NAD+ metabolism to translation control.
Nat Commun 17 ? ? (2026)
PMID: 42420298 DOI: 10.1038/s41467-026-75266-4
Primary Citation of related structures
9DPI
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