9DPD image
Deposition Date 2024-09-21
Release Date 2026-03-18
Last Version Date 2026-09-30
Entry Detail
PDB ID:
9DPD
Keywords:
TRANSLATION
Title:
Cryo-EM structure of SerRS dimer in complex with one SIRT2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli 'bl21-gold(de3)plyss ag'
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.87 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9DPD validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine--tRNA ligase, cytoplas
Gene (Uniprot):SARS1
Chain IDs:A (auth: B), B (auth: D)
Chain Length:514
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P49591 Pfam ID:PF02403, PF00587 EC:6.1.1.11
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:NAD-dependent protein deacety
Gene (Uniprot):SIRT2
Chain IDs:C
Chain Length:389
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8IXJ6 Pfam ID:PF02146 EC:2.3.1.286
Ligand Molecules
AR6
Primary Citation
A metabolite-bridged complex between SerRS and SIRT2 couples NAD+ metabolism to translation control.
Nat Commun 17 ? ? (2026)
PMID: 42420298 DOI: 10.1038/s41467-026-75266-4
Primary Citation of related structures
9DPD
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