9D1S image
Deposition Date 2024-08-07
Release Date 2025-08-13
Last Version Date 2026-03-04
Entry Detail
PDB ID:
9D1S
Keywords:
HYDROLASE
Title:
Lucilia cuprina alpha esterase 7 directed evolution round 8
Biological Source:
Source Organism(s):
Lucilia cuprina (Taxon ID: 7375)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.35 Å
R-Value Free:
0.17
R-Value Work:
0.14
R-Value Observed:
0.14
Space Group:
P 21 21 21
9D1S validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Carboxylic ester hydrolase
Gene (Uniprot):LcaE7
Chain IDs:A
Chain Length:570
Number of Molecules:1
Biological Source:Lucilia cuprina
UniProt ID:Q25252 Pfam ID:PF00135 EC:3.1.1.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
M3L A LYS modified residue
MLY A LYS modified residue
MLZ A LYS modified residue
Ligand Molecules
ACT
EDO
GOL
MPD
Primary Citation
Structural and evolutionary constraints of organophosphate resistance in dipteran carboxylesterases.
Proc.Natl.Acad.Sci.USA 123 e2517957123 e2517957123 (2026)
PMID: 41730108 DOI: 10.1073/pnas.2517957123
Primary Citation of related structures
9D1S
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