ISDA: 9CJG

Deposition Date 2024-07-06

Release Date 2025-03-12

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9CJG

Keywords:

OXIDOREDUCTASE

Title:

P450-G9 from Actinokineospora terrae, a non-canonical, serine-ligated cytochrome P450 in the ligand-free, closed conformation

Biological Source:

Source Organism(s):

Actinokineospora terrae (Taxon ID: 155974)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.85 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cytochrome P450-G9
Gene (Uniprot):SAMN04487818_101238
Chain IDs:A, B
Chain Length:411
Number of Molecules:2
Biological Source:Actinokineospora terrae

UniProt ID:A0A1H9KM06 Pfam ID:PF00067 EC:1.14.-.-

Ligand Molecules

1BO

FMT

HEM

Primary Citation

Discovery of noncanonical cytochrome P450 enzymes in nature.

Nguy, A.K.L, Ireland, K.A, Kayrouz, C.M, Caceres, J.C, Huang, J.Z, Ying, V.Y, Quaye, J.A, Greene, B.L, Davis, K.M, Seyedsayamdost, M.R.Show

Nat.Chem.Biol. ? ? ? (2026)

PMID: 42332020 DOI: 10.1038/s41589-026-02235-9

Primary Citation of related structures

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