ISDA: 9CAI

Deposition Date 2024-06-17

Release Date 2024-09-11

Last Version Date 2024-10-30

Entry Detail

PDB ID:

9CAI

Keywords:

RIBOSOME

Title:

High-resolution C. elegans 80S ribosome structure - class 1

Biological Source:

Source Organism(s):

Caenorhabditis elegans (Taxon ID: 6239)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.59 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:28S rRNA
Chain IDs:L (auth: A5)
Chain Length:3510
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Polymer Type:polyribonucleotide
Molecule:5S rRNA
Chain IDs:I (auth: A7)
Chain Length:119
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Polymer Type:polyribonucleotide
Molecule:5.8S rRNA
Chain IDs:J (auth: A8)
Chain Length:153
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-0
Chain IDs:A (auth: AA)
Chain Length:276
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P46769 Pfam ID:PF00318

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-3A
Chain IDs:D (auth: AB)
Chain Length:257
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48154 Pfam ID:PF01015

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-2
Chain IDs:F (auth: AC)
Chain Length:272
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P51403 Pfam ID:PF00333, PF03719

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-3
Chain IDs:G (auth: AD)
Chain Length:247
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48152 Pfam ID:PF07650, PF00189

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-4
Chain IDs:H (auth: AE)
Chain Length:259
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9N3X2 Pfam ID:PF08071, PF00900, PF16121

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-5
Chain IDs:V (auth: AF)
Chain Length:210
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49041 Pfam ID:PF00177

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-6
Chain IDs:DA (auth: AG)
Chain Length:246
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9NEN6 Pfam ID:PF01092

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-7
Chain IDs:MA (auth: AH)
Chain Length:194
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q23312 Pfam ID:PF01251

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-8
Chain IDs:U (auth: AI)
Chain Length:208
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48156 Pfam ID:PF01201

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-9
Chain IDs:KA (auth: AJ)
Chain Length:189
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q20228 Pfam ID:PF00163, PF01479

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Plectin/S10 N-terminal domain
Gene (Uniprot):rps-10
Chain IDs:N (auth: AK)
Chain Length:149
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O01869 Pfam ID:PF03501

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-11
Chain IDs:JA (auth: AL)
Chain Length:155
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q20206 Pfam ID:PF16205, PF00366

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-12
Chain IDs:W (auth: AM)
Chain Length:140
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49196 Pfam ID:PF01248

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-13
Chain IDs:Y (auth: AN)
Chain Length:151
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P51404 Pfam ID:PF08069, PF00312

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-14
Chain IDs:T (auth: AO)
Chain Length:152
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48150 Pfam ID:PF00411

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-15
Chain IDs:FA (auth: AP)
Chain Length:151
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9XVP0 Pfam ID:PF00203

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-16
Chain IDs:LA (auth: AQ)
Chain Length:144
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q22054 Pfam ID:PF00380

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-17
Chain IDs:M (auth: AR)
Chain Length:130
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O01692 Pfam ID:PF00833

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-18
Chain IDs:P (auth: AS)
Chain Length:154
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O18240 Pfam ID:PF00416

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-19
Chain IDs:Q (auth: AT)
Chain Length:146
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O18650 Pfam ID:PF01090

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-20
Chain IDs:CA (auth: AU)
Chain Length:117
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q8WQA8 Pfam ID:PF00338

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-21
Chain IDs:X (auth: AV)
Chain Length:88
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49197 Pfam ID:PF01249

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ribosomal Protein, Small subu
Gene (Uniprot):rps-15a
Chain IDs:O (auth: AW)
Chain Length:130
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O17218 Pfam ID:PF00410

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-23
Chain IDs:IA (auth: AX)
Chain Length:143
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q19877 Pfam ID:PF00164

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-24
Chain IDs:BA (auth: AY)
Chain Length:131
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q1XFY9 Pfam ID:PF01282

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-25
Chain IDs:Z (auth: AZ)
Chain Length:117
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P52821 Pfam ID:PF03297

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-26
Chain IDs:R (auth: Aa)
Chain Length:117
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O45499 Pfam ID:PF01283

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-27
Chain IDs:EA (auth: Ab)
Chain Length:83
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9TXP0 Pfam ID:PF01667

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-28
Chain IDs:GA (auth: Ac)
Chain Length:65
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q95Y04 Pfam ID:PF01200

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Small ribosomal subunit prote
Gene (Uniprot):rps-29
Chain IDs:AA (auth: Ad)
Chain Length:56
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P90983 Pfam ID:PF00253

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-like domain-contain
Gene (Uniprot):fau-1
Chain IDs:HA (auth: Ae)
Chain Length:130
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q18231 Pfam ID:PF00240, PF04758

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-like protein 1-ribo
Gene (Uniprot):ubl-1
Chain IDs:S (auth: Af)
Chain Length:163
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P37165 Pfam ID:PF00240, PF01599

Polymer Type:polyribonucleotide
Molecule:18S rRNA
Chain IDs:K (auth: B2)
Chain Length:1754
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-2
Chain IDs:B (auth: CA)
Chain Length:260
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9XVF7 Pfam ID:PF00181, PF03947

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-3
Chain IDs:E (auth: CB)
Chain Length:401
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P50880 Pfam ID:PF00297

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-4
Chain IDs:VA (auth: CC)
Chain Length:345
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O02056 Pfam ID:PF00573, PF14374

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-5
Chain IDs:NB (auth: CD)
Chain Length:293
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49405 Pfam ID:PF17144, PF14204

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-6
Chain IDs:XA (auth: CE)
Chain Length:217
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P47991 Pfam ID:PF01159

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-7
Chain IDs:NA (auth: CF)
Chain Length:244
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O01802 Pfam ID:PF08079, PF00327

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-7A
Chain IDs:SA (auth: CG)
Chain Length:265
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q966C6 Pfam ID:PF01248

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-9
Chain IDs:HB (auth: CH)
Chain Length:189
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q95Y90 Pfam ID:PF00347

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-10
Chain IDs:TA (auth: CI)
Chain Length:214
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q09533 Pfam ID:PF00252

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-11.2
Chain IDs:YB (auth: CJ)
Chain Length:196
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q19162 Pfam ID:PF00281, PF00673

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-13
Chain IDs:RA (auth: CL)
Chain Length:207
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P91128 Pfam ID:PF01294

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-14
Chain IDs:FB (auth: CM)
Chain Length:135
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9XVE9 Pfam ID:PF01929

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-15
Chain IDs:CB (auth: CN)
Chain Length:204
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P91374 Pfam ID:PF00827

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-16
Chain IDs:UA (auth: CO)
Chain Length:202
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q27389 Pfam ID:PF00572

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-17
Chain IDs:PB (auth: CP)
Chain Length:187
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9BL19 Pfam ID:PF00237

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-18
Chain IDs:LB (auth: CQ)
Chain Length:188
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O45946 Pfam ID:PF17135

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-19
Chain IDs:JB (auth: CR)
Chain Length:198
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O02639 Pfam ID:PF01280, PF25476

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-20
Chain IDs:OA (auth: CS)
Chain Length:180
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O44480 Pfam ID:PF01775

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-21
Chain IDs:MB (auth: CT)
Chain Length:161
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P34334 Pfam ID:PF01157

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-22
Chain IDs:QA (auth: CU)
Chain Length:130
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P52819 Pfam ID:PF01776

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-23
Chain IDs:PA (auth: CV)
Chain Length:140
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48158 Pfam ID:PF00238

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-24.1
Chain IDs:WB (auth: CW)
Chain Length:159
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O01868 Pfam ID:PF01246

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-25.2
Chain IDs:ZB (auth: CX)
Chain Length:146
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q20647 Pfam ID:PF03939, PF00276

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-26
Chain IDs:IB (auth: CY)
Chain Length:142
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q19869 Pfam ID:PF16906, PF00467

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-27
Chain IDs:OB (auth: CZ)
Chain Length:136
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P91914 Pfam ID:PF00467, PF01777

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-27a
Chain IDs:DB (auth: Ca)
Chain Length:145
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9BKU5 Pfam ID:PF00828

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:60S ribosomal protein L29
Gene (Uniprot):rpl-29
Chain IDs:KB (auth: Cb)
Chain Length:62
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O45226 Pfam ID:PF01779

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-30
Chain IDs:GB (auth: Cc)
Chain Length:115
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9XWS4 Pfam ID:PF01248

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-31
Chain IDs:UB (auth: Cd)
Chain Length:122
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9U332 Pfam ID:PF01198

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-32
Chain IDs:VB (auth: Ce)
Chain Length:134
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q22716 Pfam ID:PF01655

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-33
Chain IDs:ZA (auth: Cf)
Chain Length:124
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49180 Pfam ID:PF01247

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-34
Chain IDs:RB (auth: Cg)
Chain Length:110
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:A3QMC5 Pfam ID:PF01199

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-35
Chain IDs:WA (auth: Ch)
Chain Length:123
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P34662 Pfam ID:PF00831

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-36
Chain IDs:AB (auth: Ci)
Chain Length:104
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49181 Pfam ID:PF01158

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ribosomal protein L37
Gene (Uniprot):rpl-37.1
Chain IDs:XB (auth: Cj)
Chain Length:92
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O62388 Pfam ID:PF01907

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-38
Chain IDs:SB (auth: Ck)
Chain Length:70
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:O17570 Pfam ID:PF01781

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-39
Chain IDs:BB (auth: Cl)
Chain Length:51
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P52814 Pfam ID:PF00832

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-ribosomal protein e
Gene (Uniprot):ubq-2
Chain IDs:TB (auth: Cm)
Chain Length:128
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P49632 Pfam ID:PF00240, PF01020

Polymer Type:polypeptide(L)
Molecule:eL41
Chain IDs:QB (auth: Cn)
Chain Length:22
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-36A
Chain IDs:YA (auth: Co)
Chain Length:105
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:P48166 Pfam ID:PF00935

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):rpl-43
Chain IDs:EB (auth: Cp)
Chain Length:91
Number of Molecules:1
Biological Source:Caenorhabditis elegans

UniProt ID:Q9U2A8 Pfam ID:PF01780

Polymer Type:polyribonucleotide
Molecule:tRNA
Chain IDs:C (auth: DA)
Chain Length:76
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Polymer Type:polyribonucleotide
Molecule:mRNA
Chain IDs:AC (auth: DC)
Chain Length:10
Number of Molecules:1
Biological Source:Caenorhabditis elegans

Ligand Molecules

3HE

SPD

Primary Citation

High-resolution reconstruction of a C. elegans ribosome sheds light on evolutionary dynamics and tissue specificity.

Sehgal, E, Wohlenberg, C, Soukup, E.M, Viscardi, M.J, Serrao, V.H.B, Arribere, J.A.Show

RNA 30 1513 1528 (2024)

PMID: 39209556 DOI: 10.1261/rna.080103.124

Abstact

Caenorhabditis elegans is an important model organism for human health and disease, with foundational contributions to the understanding of gene expression and tissue patterning in animals. An invaluable tool in modern gene expression research is the presence of a high-resolution ribosome structure, though no such structure exists for C. elegans Here, we present a high-resolution single-particle cryogenic electron microscopy (cryo-EM) reconstruction and molecular model of a C. elegans ribosome, revealing a significantly streamlined animal ribosome. Many facets of ribosome structure are conserved in C. elegans, including overall ribosomal architecture and the mechanism of cycloheximide, whereas other facets, such as expansion segments and eL28, are rapidly evolving. We identify uL5 and uL23 as two instances of tissue-specific ribosomal protein paralog expression conserved in Caenorhabditis, suggesting that C. elegans ribosomes vary across tissues. The C. elegans ribosome structure will provide a basis for future structural, biochemical, and genetic studies of translation in this important animal system.

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Protein

Chemical

Disease

Primary Citation of related structures

Abstact

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