9CA9 image
Deposition Date 2024-06-17
Release Date 2025-06-18
Last Version Date 2026-08-12
Entry Detail
PDB ID:
9CA9
Keywords:
Title:
Cryo-EM structure of the human SRCAP complex in the unbound state (composite structure)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
Resolution:
3.56 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Helicase SRCAP
Gene (Uniprot):SRCAP
Chain IDs:A
Chain Length:3230
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Vacuolar protein sorting-asso
Gene (Uniprot):VPS72
Chain IDs:B
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Actin-related protein 6
Gene (Uniprot):ACTR6
Chain IDs:C
Chain Length:396
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Zinc finger HIT domain-contai
Gene (Uniprot):ZNHIT1
Chain IDs:D
Chain Length:154
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:RuvB-like 1
Gene (Uniprot):RUVBL1
Chain IDs:E, G, I
Chain Length:456
Number of Molecules:3
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:RuvB-like 2
Gene (Uniprot):RUVBL2
Chain IDs:F, H, J
Chain Length:463
Number of Molecules:3
Biological Source:Homo sapiens
Primary Citation
Structural mechanism of histone H2A.Z exchange by human SRCAP-CFDP1 holoenzyme.
Sci Adv 12 eaei7728 eaei7728 (2026)
PMID: 42536744 DOI: 10.1126/sciadv.aei7728
Primary Citation of related structures
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