9C19 image
Deposition Date 2024-05-28
Release Date 2025-07-09
Last Version Date 2026-03-04
Entry Detail
PDB ID:
9C19
Title:
Structure of human LIAS
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.58 Å
R-Value Free:
0.23
R-Value Work:
0.19
R-Value Observed:
0.20
Space Group:
P 21 21 21
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lipoyl synthase, mitochondria
Gene (Uniprot):LIAS
Chain IDs:A (auth: C), B (auth: A), C (auth: B)
Chain Length:368
Number of Molecules:3
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glycine cleavage system H pro
Gene (Uniprot):GCSH
Chain IDs:D (auth: F), E (auth: D), F (auth: E)
Chain Length:173
Number of Molecules:3
Biological Source:Homo sapiens
Primary Citation
Structural basis for catalysis by human lipoyl synthase.
Nat Commun 16 6355 6355 (2025)
PMID: 40640146 DOI: 10.1038/s41467-025-61393-x
Primary Citation of related structures
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