ISDA: 9BJ9

Deposition Date 2024-04-25

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9BJ9

Keywords:

PEPTIDE BINDING PROTEIN

Title:

Human CRL-2 ZYG11B binding to human NLRP1 Gly/N degron

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

4.20 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein zyg-11 homolog B
Gene (Uniprot):ZYG11B
Chain IDs:A
Chain Length:748
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9C0D3 Pfam ID:PF25013, PF22964

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Elongin-B
Gene (Uniprot):ELOB
Chain IDs:B
Chain Length:118
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q15370 Pfam ID:PF00240

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Elongin-C
Gene (Uniprot):ELOC
Chain IDs:C
Chain Length:96
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q15369 Pfam ID:PF03931

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cullin-2
Gene (Uniprot):CUL2
Chain IDs:D
Chain Length:779
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q13617 Pfam ID:PF00888, PF26557, PF10557 EC:2.3.2.32

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Peptide from NACHT, LRR and P
Gene (Uniprot):NLRP1
Chain IDs:E (auth: P)
Chain Length:21
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9C000

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase R
Gene (Uniprot):RBX1
Chain IDs:F (auth: R)
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62877 Pfam ID:PF12678 EC:2.3.2.27

Ligand Molecules

Primary Citation

Structure of human CRL2-ZYG11B complex binding to NLRP1 Gly/N degron

Liu, X, Gross, J.D.Show

To be published ? ? ? (?)

Primary Citation of related structures

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