ISDA: 8YUE

Deposition Date 2024-03-27

Release Date 2025-04-09

Last Version Date 2026-04-22

Entry Detail

PDB ID:

8YUE

Keywords:

MOTOR PROTEIN

Title:

Crystal structure of the kinesin-14 motor protein from Drosophila melanogaster

Biological Source:

Source Organism(s):

Drosophila melanogaster (Taxon ID: 7227)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.15 Å

R-Value Free:

0.29

R-Value Work:

0.25

R-Value Observed:

0.25

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein claret segregational
Gene (Uniprot):ncd
Mutagens:Y485K
Chain IDs:A, B
Chain Length:390
Number of Molecules:2
Biological Source:Drosophila melanogaster

UniProt ID:P20480 Pfam ID:PF00225

Ligand Molecules

ADP

PO4

Primary Citation

Structural analysis of a motor with increased mechanical output reveals new transitions in kinesin microtubule motility.

Shibata, S, Wang, M.Y, Imasaki, T, Shigematsu, H, Ugarte La Torre, D, Wei, Y, Jobichen, C, Hagio, H, Sivaraman, J, Sugita, Y, Endow, S.A, Nitta, R.Show

Sci Rep 16 487 487 (2026)

PMID: 41491787 DOI: 10.1038/s41598-025-28573-7

Primary Citation of related structures

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