8YGQ image
Deposition Date 2024-02-26
Release Date 2025-03-05
Last Version Date 2025-03-05
Entry Detail
PDB ID:
8YGQ
Keywords:
TRANSCRIPTION
Title:
Crystal structure of Human TEAD2 in complex with Cobimetinib
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.71 Å
R-Value Free:
0.25
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
C 1 2 1
8YGQ validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transcriptional enhancer fact
Gene (Uniprot):TEAD2
Chain IDs:A, B
Chain Length:226
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q15562 Pfam ID:PF17725
Ligand Molecules
EUI
PLM
Primary Citation
Crystal structure of Human TEAD2 in complex with Cobimetinib
To Be Published ? ? ? (?)
Primary Citation of related structures
8YGQ
Feedback Form
Name
Email
Institute
Feedback