ISDA: 8Y71

Deposition Date 2024-02-03

Release Date 2026-01-07

Last Version Date 2026-03-11

Entry Detail

PDB ID:

8Y71

Keywords:

MEMBRANE PROTEIN

Title:

positive allosteric modulator(BMS986187)-bound delta-opioid receptor-Gi complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Rattus norvegicus (Taxon ID: 10116)
Bos taurus (Taxon ID: 9913)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.97 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Mutagens:G203A, A326S
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):Gnb1
Chain IDs:B
Chain Length:371
Number of Molecules:1
Biological Source:Rattus norvegicus

UniProt ID:P54311 Pfam ID:PF00400, PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:68
Number of Molecules:1
Biological Source:Bos taurus

UniProt ID:P63212 Pfam ID:PF00631

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:D (auth: E)
Chain Length:248
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Delta-type opioid receptor
Gene (Uniprot):OPRD1
Chain IDs:E (auth: R)
Chain Length:523
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P41143 Pfam ID:PF00001

Ligand Molecules