8XWR image
Deposition Date 2024-01-16
Release Date 2025-01-22
Last Version Date 2025-01-22
Entry Detail
PDB ID:
8XWR
Keywords:
VIRAL PROTEIN
Title:
Crystal structure of SARS-CoV-2 3CLpro-T21I/L50F double mutant with its peptidyl substrate
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.70 Å
R-Value Free:
0.19
R-Value Work:
0.17
R-Value Observed:
0.17
Space Group:
I 1 2 1
8XWR validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Gene (Uniprot):rep
Mutagens:T21I, L50F, C145A
Chain IDs:A
Chain Length:306
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1 Pfam ID:PF05409 EC:2.7.7.48
Protein Blast
Polymer Type:polypeptide(L)
Molecule:cleaved N-terminal product of
Chain IDs:B
Chain Length:7
Number of Molecules:1
Biological Source:Severe acute respiratory syndrome coronavirus 2
Primary Citation
Crystal structure of SARS-CoV-2 3CLpro-T21I/L50F double mutant with its peptidyl substrate
To be published ? ? ? (?)
Primary Citation of related structures
8XWR
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