ISDA: 8WEN

Deposition Date 2023-09-18

Release Date 2024-09-25

Last Version Date 2026-04-08

Entry Detail

PDB ID:

8WEN

Keywords:

TOXIN

Title:

Bacteroides fragilis toxin 2

Biological Source:

Source Organism(s):

Bacteroides fragilis (Taxon ID: 817)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.97 Å

R-Value Free:

0.20

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Metalloprotease
Chain IDs:A (auth: C), B (auth: A)
Chain Length:397
Number of Molecules:2
Biological Source:Bacteroides fragilis

UniProt ID:A0A0E2AWB8 Pfam ID:PF16376, PF13688

Ligand Molecules

Primary Citation

Mechanistic diversity of Bacteroides fragilis toxins and neutralization with single domain antibody.

Guo, Y, Ouyang, Z, He, W, Qin, Q, Zhang, J, Yu, T, Jiao, M, Hwang, P.M, Zheng, F, Muyldermans, S, Wen, Y.Show

Cell Chem Biol 33 102 116.e6 (2026)

PMID: 41544614 DOI: 10.1016/j.chembiol.2025.12.009

Primary Citation of related structures

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