8VS7 image
Deposition Date 2024-01-23
Release Date 2024-09-18
Last Version Date 2026-04-01
Entry Detail
PDB ID:
8VS7
Keywords:
Title:
Crystal structure of ADI-19425 Fab in complex with anti-idiotypic 2C1 Fab
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.41 Å
R-Value Free:
0.25
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 1 21 1
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2C1 Heavy Chain
Chain IDs:B (auth: A)
Chain Length:238
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:2C1 Light Chain
Chain IDs:A (auth: B)
Chain Length:214
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:ADI-19425 Heavy Chain
Chain IDs:C (auth: H)
Chain Length:227
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:ADI-19425 Light Chain
Chain IDs:D (auth: L)
Chain Length:218
Number of Molecules:1
Biological Source:Homo sapiens
Primary Citation
Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies.
Cell Rep 43 114811 114811 (2024)
PMID: 39383036 DOI: 10.1016/j.celrep.2024.114811
Primary Citation of related structures
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