ISDA: 8V2R

Deposition Date 2023-11-23

Release Date 2024-11-27

Last Version Date 2026-07-15

Entry Detail

PDB ID:

8V2R

Keywords:

DNA BINDING PROTEIN

Title:

CHMP1B/IST1 ssDNA bound copolymer" to match the formatting of the other associated entries (8V2S & 8V2Q)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.01 Å

Aggregation State:

FILAMENT

Reconstruction Method:

HELICAL

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Charged multivesicular body p
Gene (Uniprot):CHMP1B
Mutagens:M136V
Chain IDs:A
Chain Length:199
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q7LBR1 Pfam ID:PF03357

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:IST1 homolog
Gene (Uniprot):IST1
Chain IDs:B
Chain Length:364
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P53990 Pfam ID:PF03398

Ligand Molecules

Primary Citation

ESCRT-III Assembles Around Mis-segregated DNA to Engage NoCut

Talledge, N, Glover, J, McCullough, J, Alian, A, Sadler, J.B.A, Dempsey, N, Laughlin, T.G, Nguyen, H.C, Wenzel, D, Lalonde, M.S, Ventimiglia, L.N, LaJoie, D, Iwasa, J, Starling, T, Padilla-Parra, S, Ullman, K.S, Frost, A, Sundquist, W.I, Martin-Serrano, J.Show

Nat.Struct.Mol.Biol. ? ? ? (2026)

DOI: 10.1038/s41594-026-01841-4

Primary Citation of related structures

Feedback Form