8S1O image
Deposition Date 2024-02-15
Release Date 2025-09-03
Last Version Date 2026-03-18
Entry Detail
PDB ID:
8S1O
Keywords:
SIGNALING PROTEIN
Title:
Crystal structure of human Rac1-GDP-Pi
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.27 Å
R-Value Free:
0.26
R-Value Work:
0.20
R-Value Observed:
0.21
Space Group:
C 2 2 21
8S1O validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Ras-related C3 botulinum toxi
Gene (Uniprot):RAC1
Chain IDs:A
Chain Length:177
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P63000 Pfam ID:PF00071 EC:3.6.5.2
Ligand Molecules
GDP
MG
PO4
Primary Citation
The cytokinesis regulator RacGAP1 is a Rac1-specific GAP on membranes.
Protein Sci. 35 e70488 e70488 (2026)
PMID: 41676911 DOI: 10.1002/pro.70488
Primary Citation of related structures
8S1O
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