ISDA: 8OW4

Deposition Date 2023-04-27

Release Date 2023-07-26

Last Version Date 2024-02-07

Entry Detail

PDB ID:

8OW4

Keywords:

DNA BINDING PROTEIN

Title:

2.75 angstrom crystal structure of human NFAT1 with bound DNA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.75 Å

R-Value Free:

0.27

R-Value Work:

0.21

Space Group:

I 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear factor of activated T
Gene (Uniprot):NFATC2
Chain IDs:A, F (auth: B)
Chain Length:298
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q13469 Pfam ID:PF00554, PF16179

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*AP*AP*CP*TP*AP*TP*
Chain IDs:C, E (auth: H)
Chain Length:15
Number of Molecules:2
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*TP*GP*CP*TP*GP*
Chain IDs:B (auth: W), D (auth: G)
Chain Length:15
Number of Molecules:2
Biological Source:Homo sapiens

Primary Citation

2.75 angstrom crystal structure of human NFAT1 with bound DNA

Lopez-Sagaseta, J, Erausquin, E, Hernandez-Morales, S, Urdiciain, A, Lasarte, J.J, Lozano, T.Show

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Primary Citation of related structures

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