8KET image
Deposition Date 2023-08-13
Release Date 2025-02-19
Last Version Date 2025-07-23
Entry Detail
PDB ID:
8KET
Keywords:
Title:
Cryo-EM structure of HRD1-SEL1LFL-XTP3B complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:E3 ubiquitin-protein ligase s
Gene (Uniprot):SYVN1
Chain IDs:A, B
Chain Length:617
Number of Molecules:2
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Protein sel-1 homolog 1
Gene (Uniprot):SEL1L
Chain IDs:E (auth: C)
Chain Length:547
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Endoplasmic reticulum lectin
Gene (Uniprot):ERLEC1
Chain IDs:C (auth: F)
Chain Length:483
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:ANA
Chain IDs:D (auth: H)
Chain Length:3
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Structural insights into the human HRD1 ubiquitin ligase complex
Nat Commun 16 6007 ? (2025)
DOI: 10.1038/s41467-025-61143-z
Primary Citation of related structures
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