ISDA: 8J7S

Deposition Date 2023-04-28

Release Date 2024-03-06

Last Version Date 2024-03-06

Entry Detail

PDB ID:

8J7S

Keywords:

IMMUNE SYSTEM/RNA/DNA

Title:

Structure of the SPARTA complex

Biological Source:

Source Organism(s):

Maribacter polysiphoniae (Taxon ID: 429344)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.84 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Piwi domain-containing protei
Gene (Uniprot):LX92_01809
Chain IDs:A, E, I, M
Chain Length:506
Number of Molecules:4
Biological Source:Maribacter polysiphoniae

UniProt ID:A0A316E3U6

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:TIR domain-containing protein
Gene (Uniprot):LX92_01810
Chain IDs:B, F, J, N
Chain Length:418
Number of Molecules:4
Biological Source:Maribacter polysiphoniae

UniProt ID:A0A316E683 Pfam ID:PF13676

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*UP*GP*AP*CP*GP*GP
Chain IDs:C, G, K, O
Chain Length:19
Number of Molecules:4
Biological Source:Maribacter polysiphoniae

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*AP*AP*TP*AP*GP
Chain IDs:D, H, L, P
Chain Length:24
Number of Molecules:4
Biological Source:Maribacter polysiphoniae

Ligand Molecules

Primary Citation

Cryo-EM structure of the ssDNA-activated SPARTA complex.

Guo, M, Zhu, Y, Lin, Z, Yang, D, Zhang, A, Guo, C, Huang, Z.Show

Cell Res. 33 731 734 (2023)

PMID: 37491603 DOI: 10.1038/s41422-023-00850-y

Primary Citation of related structures

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