ISDA: 8H4M

Deposition Date 2022-10-10

Release Date 2023-10-18

Last Version Date 2026-03-04

Entry Detail

PDB ID:

8H4M

Keywords:

IMMUNE SYSTEM

Title:

Crystal Structure of GTP-bound Irgb6_T95D mutant

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.68 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:T-cell-specific guanine nucle
Gene (Uniprot):Tgtp2
Mutagens:T95D
Chain IDs:A
Chain Length:417
Number of Molecules:1
Biological Source:Mus musculus

UniProt ID:Q3T9E4 Pfam ID:PF05049

Ligand Molecules

GTP

Primary Citation

Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I

Okuma, H, Saijo-Hamano, Y, Sherif, A.A, Hashizaki, E, Sakai, N, Kato, K, Imasaki, T, Nitta, E, Sasai, M, Kosako, H, Standley, D.M, Yamamoto, M, Nitta, R.Show

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Primary Citation of related structures

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