ISDA: 8GML

Deposition Date 2023-03-26

Release Date 2023-09-20

Last Version Date 2023-09-20

Entry Detail

PDB ID:

8GML

Keywords:

TRANSFERASE/DNA

Title:

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dG

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.57 Å

R-Value Free:

0.26

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 61

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA polymerase eta
Gene (Uniprot):POLH
Chain IDs:A
Chain Length:432
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9Y253 Pfam ID:PF00817, PF21704, PF11799 EC:2.7.7.7

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*AP*GP*TP*GP*TP*GP*
Chain IDs:C (auth: P)
Chain Length:8
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*GP*CP*TP*CP*AP
Chain IDs:B (auth: T)
Chain Length:12
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

B7P

Primary Citation

Crystal structure of human DNA polymerase eta incorporating 5F-dUTP across dA

Jung, H.Show

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