8D7K image
Deposition Date 2022-06-07
Release Date 2023-06-14
Last Version Date 2024-10-23
Entry Detail
PDB ID:
8D7K
Keywords:
HYDROLASE/INHIBITOR, PROTEIN BINDING
Title:
Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus
Biological Source:
Source Organism(s):
Staphylococcus aureus subsp. aureus (Taxon ID: 158878)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
3.10 Å
R-Value Free:
0.25
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
P 1 21 1
8D7K validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Neutrophil elastase
Gene (Uniprot):ELANE
Chain IDs:C (auth: A), F (auth: D), I (auth: G), L (auth: J)
Chain Length:218
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P08246 Pfam ID:PF00089 EC:3.4.21.37
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Extracellular Adherence Prote
Gene (Uniprot):map
Chain IDs:B, E, H, K
Chain Length:100
Number of Molecules:4
Biological Source:Staphylococcus aureus subsp. aureus
UniProt ID:Q99QS1 Pfam ID:PF03642
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cathepsin G, C-terminal trunc
Gene (Uniprot):CTSG
Chain IDs:A (auth: C), D (auth: F), G (auth: I), J (auth: L)
Chain Length:223
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P08311 Pfam ID:PF00089 EC:3.4.21.20
Ligand Molecules
NA
Primary Citation
Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus
To be published ? ? ? (?)
Primary Citation of related structures
8D4Q
8D4S
8D4U
8D4V
8D7I
Feedback Form
Name
Email
Institute
Feedback