8CA6 image
Deposition Date 2023-01-24
Release Date 2024-08-07
Last Version Date 2024-08-07
Entry Detail
PDB ID:
8CA6
Keywords:
ANTIVIRAL PROTEIN
Title:
Crystal structure of SARS-CoV-2 Mpro-Q189K mutant, free enzyme
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.92 Å
R-Value Free:
0.29
R-Value Work:
0.23
Space Group:
P 1 21 1
8CA6 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Non-structural protein 11
Chain IDs:A (auth: AAA), B (auth: BBB)
Chain Length:306
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1
Primary Citation
13b-K and Nirmatrelvir Resistance Mutations of SARS-CoV-2 Main Protease: Structural, Biochemical, and Biophysical Characterization of Free Enzymes and Inhibitor Complexes
Crystals 15 ? ? (2025)
DOI: 10.3390/cryst15090758
Primary Citation of related structures
8CA6
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