ISDA: 8BG3

Deposition Date 2022-10-27

Release Date 2023-11-08

Last Version Date 2026-03-04

Entry Detail

PDB ID:

8BG3

Keywords:

PROTEIN BINDING

Title:

Crystal structure of the SARS-CoV-2 S RBD in complex with pT1610 scFV

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Drosophila melanogaster

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:pT1610 single-chain Fv
Chain IDs:A, C
Chain Length:252
Number of Molecules:2
Biological Source:Homo sapiens

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Spike protein S1
Gene (Uniprot):S
Chain IDs:B, D
Chain Length:199
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

UniProt ID:P0DTC2 Pfam ID:PF09408

Ligand Molecules

NAG

Primary Citation

Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses?

Stein, C.S, Hansen, G, Ssebyatika, G.L, Stroeh, L, Benecke, T, Menz, S, Waldmann, J.-Y, Vollmer, B, Tipp, S, Ochulor, O, Herold, E, Schwarzloh, B, Mutschall, D, Zischke, J.-Y, Cordes, A, Puppe, W, Schneider, T, Hinrichs, I, Blasczyk, R, Kleine-Weber, H, Hoffmann, M, Hoeper, M, Kaiser, F.K, Gonzalez-Hernandez, M, Armando, F.K, Ciurkiewicz, M, Beythien, G, Poehlmann, S, Baumgaertner, W, Gruenewald, K, Osterhaus, A, Schulz, T, Krey, T.Show

To be published ? ? ? (?)

Primary Citation of related structures

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