ISDA: 8AND

Deposition Date 2022-08-05

Release Date 2024-04-17

Last Version Date 2026-06-03

Entry Detail

PDB ID:

8AND

Keywords:

HYDROLASE INHIBITOR

Title:

Domain swapped dimer of smolstatin (stefin) from Sphaerospora molnari

Biological Source:

Source Organism(s):

Sphaerospora molnari (Taxon ID: 182359)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.99 Å

R-Value Free:

0.24

R-Value Work:

0.19

Space Group:

P 1 21 1

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Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Smolstatin
Chain IDs:A (auth: AAA), B (auth: BBB)
Chain Length:100
Number of Molecules:2
Biological Source:Sphaerospora molnari

Ligand Molecules

EDO

Primary Citation

Smolstatin1, a unique cystatin-like stefin of Sphaerospora molnari, is essential for parasite development

Bartosova-Sojkova, P, Dobai, T, Kyslik, J, Havlickova, P, Vancova, M, Picard-Sanchez, M.A, Qadiri, S.S.N, Martins, L.A, Urbanova, V, Kosakyan, A, Bily, T, Kale, D, Kotal, J, Chan, J.T.H, Korytar, T, Ludwig, J, Smatanova, I.K, Holzer, A.S, Sojka, D.Show

Curr Res Microb Sci ? 100611 ? (2026)

DOI: 10.1016/j.crmicr.2026.100611

Primary Citation of related structures

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