8ANC image
Deposition Date 2022-08-05
Release Date 2023-08-16
Last Version Date 2026-04-01
Entry Detail
PDB ID:
8ANC
Keywords:
PEPTIDE BINDING PROTEIN
Title:
14-3-3 sigma sirtuin-3 phospho-peptide complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.11 Å
R-Value Free:
0.14
R-Value Work:
0.12
R-Value Observed:
0.12
Space Group:
C 2 2 21
8ANC validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Gene (Uniprot):SFN
Chain IDs:A
Chain Length:236
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P31947 Pfam ID:PF00244
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:NAD-dependent protein deacety
Gene (Uniprot):SIRT3
Chain IDs:B (auth: P)
Chain Length:11
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9NTG7 EC:2.3.1.24
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SEP B SER modified residue
Ligand Molecules
CA
CL
MG
Primary Citation
Potential 14-3-3 binding sites in sirtuins reveal extended phosphosite-recognition modes.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 82 32 40 (2026)
PMID: 41410196 DOI: 10.1107/S2053230X25010908
Primary Citation of related structures
1YWT
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