ISDA: 7ZKU

Deposition Date 2022-04-13

Release Date 2023-10-25

Last Version Date 2026-03-04

Entry Detail

PDB ID:

7ZKU

Keywords:

ANTIVIRAL PROTEIN

Title:

Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'd<carba>GMP)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.70 Å

R-Value Free:

0.24

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Stimulator of interferon prot
Chain IDs:A, B
Chain Length:204
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q86WV6 Pfam ID:PF15009

Ligand Molecules

JLU

Primary Citation

Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-2'd<carba>GMP)

Klima, M, Smola, M, Boura, E.Show

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Primary Citation of related structures

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