7TAG image
Deposition Date 2021-12-20
Release Date 2023-01-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
7TAG
Keywords:
VIRUS/INHIBITOR
Title:
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril
Biological Source:
Source Organism(s):
enterovirus D68 (Taxon ID: 42789)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
7TAG validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:viral protein 1
Chain IDs:A
Chain Length:296
Number of Molecules:1
Biological Source:enterovirus D68
UniProt ID:A0A097BW12 Pfam ID:PF22663, PF00073, PF02226
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:viral protein 2
Chain IDs:C (auth: B)
Chain Length:238
Number of Molecules:1
Biological Source:enterovirus D68
UniProt ID:A0A097BW12 Pfam ID:PF22663, PF00073, PF02226
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:viral protein 3
Chain IDs:B (auth: C)
Chain Length:247
Number of Molecules:1
Biological Source:enterovirus D68
UniProt ID:A0A097BW12 Pfam ID:PF22663, PF00073, PF02226
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:viral protein 4
Chain IDs:D
Chain Length:68
Number of Molecules:1
Biological Source:enterovirus D68
UniProt ID:A0A097BW12 Pfam ID:PF22663, PF00073, PF02226
Ligand Molecules
W11
Primary Citation
Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5.
Antiviral Res. 216 105654 105654 (2023)
PMID: 37327878 DOI: 10.1016/j.antiviral.2023.105654
Primary Citation of related structures
7TAG
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