ISDA: 7T1E

Deposition Date 2021-12-01

Release Date 2022-12-14

Last Version Date 2024-10-16

Entry Detail

PDB ID:

7T1E

Keywords:

IMMUNE SYSTEM

Title:

Structure of monomeric and dimeric human CCL20

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.46 Å

R-Value Free:

0.17

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 32 2 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:C-C motif chemokine 20
Gene (Uniprot):CCL20
Chain IDs:A, B, C, D, E
Chain Length:70
Number of Molecules:5
Biological Source:Homo sapiens

UniProt ID:P78556 Pfam ID:PF00048

Ligand Molecules

GOL

PEG

SIN

Primary Citation

The Chemokine, CCL20, and Its Receptor, CCR6, in the Pathogenesis and Treatment of Psoriasis and Psoriatic Arthritis

Shi, Z.R, Mabuchi, T, Riutta, S.J, Wu, X, Peterson, F.C, Volkman, B.F, Hwang, S.T.Show

J Psoriasis Psoriatic Arthritis 8 107 117 (2023)

DOI: 10.1177/24755303231159106

Primary Citation of related structures

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