ISDA: 7S7T

Deposition Date 2021-09-17

Release Date 2021-10-13

Last Version Date 2026-03-18

Entry Detail

PDB ID:

7S7T

Keywords:

FLUORESCENT PROTEIN

Title:

iNicSnFR3a Nicotine Sensor comprising Periplasmic Binding sequence plus Fluorescent Sequence with varenicline bound

Biological Source:

Source Organism(s):

Thermoanaerobacter sp. X513 (Taxon ID: 573062)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.20 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.19

Space Group:

P 61

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:iNicSnFR 3.0 Fluorescent Nico
Chain IDs:A
Chain Length:539
Number of Molecules:1
Biological Source:Thermoanaerobacter sp. X513

UniProt ID:7S7T

Ligand Molecules

IOD

QMR

Primary Citation

Correction: Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands.

Nichols, A.L, Blumenfeld, Z, Fan, C, Luebbert, L, Blom, A.E.M, Cohen, B.N, Marvin, J.S, Borden, P.M, Kim, C.H, Muthusamy, A.K, Shivange, A.V, Knox, H.J, Campello, H.R, Wang, J.H, Dougherty, D.A, Looger, L.L, Gallagher, T, Rees, D.C, Lester, H.A.Show

Elife 11 ? ? (2022)

PMID: 36520038 DOI: 10.7554/eLife.85479

Primary Citation of related structures

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