7R2K image
Deposition Date 2022-02-04
Release Date 2023-08-16
Last Version Date 2025-07-09
Entry Detail
PDB ID:
7R2K
Keywords:
ANTIVIRAL PROTEIN
Title:
elongated Cascade complex from type I-A CRISPR-Cas system
Biological Source:
Source Organism(s):
Pyrococcus furiosus DSM 3638 (Taxon ID: 186497)
Escherichia coli (Taxon ID: 562)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
7R2K validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:CRISPR-associated helicase Ca
Gene (Uniprot):cas3
Chain IDs:A
Chain Length:651
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:A0A5C0XNV5 Pfam ID:PF00270, PF22590
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cas11a
Gene (Uniprot):PF0643
Chain IDs:B (auth: C), D (auth: E), E (auth: F), F (auth: G), G (auth: H), H (auth: I), I (auth: J)
Chain Length:108
Number of Molecules:7
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:Q8U332
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*AP*CP*AP*AP*GP
Chain IDs:C (auth: D)
Chain Length:9
Number of Molecules:1
Biological Source:Escherichia coli
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cas7a
Gene (Uniprot):PF0642
Chain IDs:J (auth: K), K (auth: L), L (auth: M), M (auth: N), N (auth: O), O (auth: P), Q (auth: R), S (auth: T), U (auth: V), V (auth: W)
Chain Length:336
Number of Molecules:10
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:Q8U333 Pfam ID:PF01905
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:CRISPR-associated endonucleas
Gene (Uniprot):cas3
Chain IDs:P (auth: Q)
Chain Length:238
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:Q8U336 Pfam ID:PF18019 EC:3.1.-.-
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Type I-A CRISPR-associated pr
Gene (Uniprot):cas5a
Chain IDs:R (auth: S)
Chain Length:256
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:A0A5C0XNV9
Polymer Type:polyribonucleotide
Molecule:crRNA (57-MER)
Chain IDs:T (auth: U)
Chain Length:57
Number of Molecules:1
Biological Source:Escherichia coli
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*CP*CP*C)-3')
Chain IDs:W (auth: X)
Chain Length:4
Number of Molecules:1
Biological Source:Escherichia coli
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cas8
Gene (Uniprot):PF0637
Chain IDs:X (auth: Y)
Chain Length:341
Number of Molecules:1
Biological Source:Pyrococcus furiosus DSM 3638
UniProt ID:Q8U338 Pfam ID:PF09703
Ligand Molecules
NI
Primary Citation
Structural snapshots for an atypic type I CRISPR-Cas system
To be published ? ? ? (?)
Primary Citation of related structures
7R2K
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