7PA9 image
Deposition Date 2021-07-29
Release Date 2023-02-08
Last Version Date 2026-10-21
Entry Detail
PDB ID:
7PA9
Keywords:
VIRAL PROTEIN
Title:
JC polyomavirus VP1 in complex with Fab 98D3
Biological Source:
Source Organism(s):
JC polyomavirus (Taxon ID: 10632)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli, Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.75 Å
R-Value Free:
0.26
R-Value Work:
0.20
Space Group:
P 21 21 21
7PA9 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Major capsid protein VP1
Chain IDs:A (auth: AAA), B (auth: BBB), C (auth: CCC), D (auth: DDD), E (auth: EEE), F (auth: FFF), G (auth: GGG), H (auth: HHH), I (auth: III), J (auth: JJJ)
Chain Length:272
Number of Molecules:10
Biological Source:JC polyomavirus
UniProt ID:P03089 Pfam ID:PF00718
Polymer Type:polypeptide(L)
Molecule:Fab 98D3 VH
Chain IDs:K (auth: KKK), M (auth: MMM), O (auth: OOO), Q (auth: QQQ), T (auth: TTT), V (auth: VVV), X (auth: XXX), Y (auth: YYY), BA (auth: bbb), CA (auth: ccc)
Chain Length:404
Number of Molecules:10
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Fab 98D3 VL
Chain IDs:L (auth: LLL), N (auth: NNN), P (auth: PPP), R (auth: RRR), S (auth: SSS), U (auth: UUU), W (auth: WWW), Z (auth: ZZZ), AA (auth: aaa), DA (auth: ddd)
Chain Length:212
Number of Molecules:10
Biological Source:Homo sapiens
Primary Citation
Structural characterization of human neutralizing antibodies against JC and BK polyomaviruses.
Proc.Natl.Acad.Sci.USA 123 e2603048123 e2603048123 (2026)
PMID: 42406959 DOI: 10.1073/pnas.2603048123
Primary Citation of related structures
7PA9
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