ISDA: 7P5U

Deposition Date 2021-07-14

Release Date 2022-07-27

Last Version Date 2026-03-25

Entry Detail

PDB ID:

7P5U

Keywords:

SIGNALING PROTEIN

Title:

Neuropilin-b1 in a complex with a VEGFB-derived peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.60 Å

R-Value Free:

0.21

R-Value Work:

0.18

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Neuropilin-1
Gene (Uniprot):NRP1
Chain IDs:A (auth: AAA), B (auth: BBB)
Chain Length:158
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O14786 Pfam ID:PF00754

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:MGC0122
Chain IDs:C (auth: CCC), D (auth: EEE)
Chain Length:13
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:7P5U

Primary Citation

Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1.

Mota, F, Yelland, T, Hutton, J.A, Parker, J, Patsiarika, A, Chan, A.W.E, O'Leary, A, Fotinou, C, Martin, J.F, Zachary, I.C, Djordjevic, S, Frankel, P, Selwood, D.L.Show

Chembiochem 23 e202100463 e202100463 (2022)

PMID: 34647407 DOI: 10.1002/cbic.202100463

Primary Citation of related structures

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