7ORG image
Deposition Date 2021-06-05
Release Date 2022-06-22
Last Version Date 2024-10-16
Entry Detail
PDB ID:
7ORG
Keywords:
SIGNALING PROTEIN
Title:
Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ162
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.80 Å
R-Value Free:
0.20
R-Value Work:
0.15
R-Value Observed:
0.16
Space Group:
C 2 2 21
7ORG validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Gene (Uniprot):SFN
Chain IDs:A
Chain Length:253
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P31947 Pfam ID:PF00244
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyclin-dependent kinase inhib
Gene (Uniprot):CDKN1B
Chain IDs:B (auth: P)
Chain Length:12
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P46527
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
CSO A CYS modified residue
TPO B THR modified residue
Ligand Molecules
09W
CL
MG
Primary Citation
A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To be published ? ? ? (?)
Primary Citation of related structures
7ORG
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