7OPW image
Deposition Date 2021-06-01
Release Date 2022-06-08
Last Version Date 2025-10-01
Entry Detail
PDB ID:
7OPW
Keywords:
SIGNALING PROTEIN
Title:
Ternary complex of 14-3-3 sigma, Estrogen Receptor alfa phosphopeptide, and WQ136
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.81 Å
R-Value Free:
0.22
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
C 2 2 21
7OPW validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:14-3-3 protein sigma
Gene (Uniprot):SFN
Chain IDs:A
Chain Length:253
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P31947 Pfam ID:PF00244
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Estrogen receptor
Gene (Uniprot):ESR1
Chain IDs:B
Chain Length:15
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P03372 Pfam ID:PF12743
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
TPO B THR modified residue
Ligand Molecules
0AW
BME
CL
MG
Primary Citation
A crystallography-based study of fragment extensions into the 14-3-3 binding groove
To be published ? ? ? (?)
Primary Citation of related structures
7OPW
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