ISDA: 7LGO

Deposition Date 2021-01-20

Release Date 2021-01-27

Last Version Date 2026-07-29

Entry Detail

PDB ID:

7LGO

Keywords:

RNA BINDING PROTEIN

Title:

Crystal structure of the nucleic acid binding domain (NAB) of Nsp3 from SARS-CoV-2

Biological Source:

Source Organism(s):

Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.45 Å

R-Value Free:

0.31

R-Value Work:

0.26

R-Value Observed:

0.26

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Non-structural protein 3
Gene (Uniprot):rep
Chain IDs:A, B
Chain Length:115
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

UniProt ID:P0DTD1 Pfam ID:PF16251 EC:2.7.7.48

Primary Citation

Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5' UTR of the viral genome.

Lemak, S, Skarina, T, Patel, D.T, Stogios, P.J, Savchenko, A.Show

Microbiol Spectr 13 e0287124 e0287124 (2025)

PMID: 40621910 DOI: 10.1128/spectrum.02871-24

Primary Citation of related structures

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