ISDA: 7JZ0

Deposition Date 2020-09-01

Release Date 2020-09-16

Last Version Date 2026-04-01

Entry Detail

PDB ID:

7JZ0

Keywords:

VIRAL PROTEIN/RNA

Title:

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

Biological Source:

Source Organism(s):

Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.15 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 32 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:2'-O-methyltransferase
Gene (Uniprot):rep
Chain IDs:A, C
Chain Length:300
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

UniProt ID:P0DTD1 Pfam ID:PF06460, PF09401 EC:2.7.7.48

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Non-structural protein 10
Gene (Uniprot):rep
Chain IDs:B, D
Chain Length:141
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

UniProt ID:P0DTD1 Pfam ID:PF06460, PF09401 EC:2.7.7.48

Polymer Type:polyribonucleotide
Molecule:RNA (5'-D(*(M7G))-R(P*(A2M)P*
Chain IDs:E, F
Chain Length:7
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2

Ligand Molecules