ISDA: 6U1S

Deposition Date 2019-08-16

Release Date 2020-08-19

Last Version Date 2024-03-20

Entry Detail

PDB ID:

6U1S

Keywords:

DE NOVO PROTEIN

Title:

Cryo-EM structure of a de novo designed 16-helix transmembrane nanopore, TMHC8_R.

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

7.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:de novo designed 16-helix tra
Chain IDs:A, B, C (auth: D), D (auth: F), E (auth: H), F (auth: J), G (auth: L), H (auth: N)
Chain Length:310
Number of Molecules:8
Biological Source:synthetic construct

UniProt ID:6U1S

Ligand Molecules

Primary Citation

Computational Design of Transmembrane Channels

Xu, C, Lu, P, Gamal El-Din, T.M, Pei, X, Johnson, M.J, Uyeda, A, Bick, M.J, Jiang, D, Hsia, Y, Brunette, T.J, Ma, D, Lynch, E, Boyken, S.E, Huang, P, Stewart, L, Kollman, J.K, Luisi, B.F, Matsuura, T, Catterall, W.A, Baker, D.Show

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