6SU0 image
Deposition Date 2019-09-12
Release Date 2020-02-19
Last Version Date 2024-01-24
Entry Detail
PDB ID:
6SU0
Keywords:
SUGAR BINDING PROTEIN
Title:
Crystal structure of dimethylated RSLex in complex with cucurbit[7]uril
Biological Source:
Source Organism(s):
Ralstonia solanacearum (Taxon ID: 305)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.98 Å
R-Value Free:
0.31
R-Value Work:
0.24
R-Value Observed:
0.25
Space Group:
C 1 2 1
6SU0 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fucose-binding lectin protein
Chain IDs:A, B, C, D, E, F, G (auth: I), H (auth: J), I (auth: K), J (auth: M), K (auth: N), L (auth: O)
Chain Length:89
Number of Molecules:12
Biological Source:Ralstonia solanacearum
UniProt ID:Q8XXK6 Pfam ID:PF07938
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
MLY A LYS modified residue
Ligand Molecules
MFU
NA
QQ7
Primary Citation
Engineered assembly of a protein-cucurbituril biohybrid.
Chem. Commun. (Camb.) 56 360 363 (2020)
PMID: 31825399 DOI: 10.1039/c9cc07198a

Abstact

A crystalline biohybrid with a 4 : 1 protein : cucurbituril mass ratio is presented. This result was achieved by engineering additional cucurbit[7]uril (Q7) binding sites into a β-propeller protein. In contrast to the parent protein, Q7-controlled assembly of the engineered variant occurred in solution, as evidenced by NMR and SAXS measurements.

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Protein

Chemical

Disease

Primary Citation of related structures
6SU0
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