ISDA: 6SM5

Deposition Date 2019-08-21

Release Date 2021-01-13

Last Version Date 2024-01-24

Entry Detail

PDB ID:

6SM5

Keywords:

BIOSYNTHETIC PROTEIN

Title:

MbC/SHP1-C-SH2 complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.75 Å

R-Value Free:

0.27

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tyrosine-protein phosphatase
Gene (Uniprot):PTPN6
Chain IDs:A
Chain Length:120
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P29350 Pfam ID:PF00017 EC:3.1.3.48

Polymer Type:polypeptide(L)
Molecule:MbC (monobody targeting SHP1-
Chain IDs:B
Chain Length:93
Number of Molecules:1
Biological Source:synthetic construct

Primary Citation

MbC/SHP1-C-SH2 complex

Hantschel, O.Show

To be published ? ? ? (?)

Primary Citation of related structures

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