ISDA: 6QSG

Deposition Date 2019-02-20

Release Date 2020-03-18

Last Version Date 2024-01-24

Entry Detail

PDB ID:

6QSG

Keywords:

DE NOVO PROTEIN

Title:

Crystal structure of the hybrid bioinorganic complex of Pizza6S and Keggin (STA)

Biological Source:

Source Organism(s):

Synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.15 Å

R-Value Free:

0.18

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Pizza6S
Chain IDs:A
Chain Length:256
Number of Molecules:1
Biological Source:Synthetic construct

UniProt ID:6QSG

Ligand Molecules

SIW

Primary Citation

Hybrid assemblies of a symmetric designer protein and polyoxometalates with matching symmetry.

Vandebroek, L, Noguchi, H, Kamata, K, Tame, J.R.H, Van Meervelt, L, Parac-Vogt, T.N, Voet, A.R.D.Show

Chem. Commun. (Camb.) 56 11601 11604 (2020)

PMID: 32869783 DOI: 10.1039/d0cc05071g

Abstact

Novel bioinorganic hybrid materials based on proteins and inorganic clusters have enormous potential for the development of hybrid catalysts that synergistically combine properties of both materials. Here we report the creation of hybrid assemblies between a computationally designed symmetrical protein Pizza6-S and different polyoxometalates with matching symmetry: the tellurotungstic Anderson-Evans (Na6[TeW6O24]·22H2O) (TEW); Keggin (H4[SiW12O40]·6H2O) (STA); and 1 : 2 CeIII-substituted Keggin (K11[CeIII[PW11O39]2]·20H2O) (Ce-K). This results in the formation of complexes with clearly defined stoichiometries in solution. Crystal structures validate the complexes as building blocks for the formation of larger assemblies.

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Primary Citation of related structures

Abstact

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