ISDA: 6N7M

Deposition Date 2018-11-27

Release Date 2018-12-12

Last Version Date 2026-02-18

Entry Detail

PDB ID:

6N7M

Keywords:

UNKNOWN FUNCTION

Title:

1.78 Angstrom Resolution Crystal Structure of Hypothetical Protein CD630_05490 from Clostridioides difficile 630.

Biological Source:

Source Organism(s):

Peptoclostridium difficile (strain 630) (Taxon ID: 272563)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.78 Å

R-Value Free:

0.28

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hypothetical Protein CD630_05
Gene (Uniprot):CD630_05490
Chain IDs:A, B, C, D
Chain Length:110
Number of Molecules:4
Biological Source:Peptoclostridium difficile (strain 630)

UniProt ID:Q188Z7

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
MSE	A	MET	modified residue

Primary Citation

A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.

Rosas-Lemus, M, Dey, S, Minasov, G, Tan, K, Anderson, S.M, Brunzelle, J, Nocadello, S, Shabalin, I, Filippova, E, Halavaty, A, Kim, Y, Maltseva, N, Osipiuk, J, Minor, W, Joachimiak, A, Savchenko, A, Anderson, W.F, Satchell, K.J.F.Show

Microbiol Resour Announc 12 e0050723 e0050723 (2023)

PMID: 37747257 DOI: 10.1128/MRA.00507-23

Abstact

Clostridioides difficile causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.

Legend

Protein

Chemical

Disease

Primary Citation of related structures

Abstact

Feedback Form