ISDA: 6HRH

Deposition Date 2018-09-27

Release Date 2018-11-07

Last Version Date 2024-01-24

Entry Detail

PDB ID:

6HRH

Keywords:

OXIDOREDUCTASE

Title:

Structure of human erythroid-specific 5'-aminolevulinate synthase, ALAS2

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.30 Å

R-Value Free:

0.23

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:5-aminolevulinate synthase, e
Gene (Uniprot):ALAS2
Chain IDs:A (auth: B), B (auth: A)
Chain Length:469
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P22557 Pfam ID:PF00155 EC:2.3.1.37

Ligand Molecules

PLP

Primary Citation

Structure of human erythroid-specific 5'-aminolevulinate synthase, ALAS2

Bailey, H.J, Shrestha, L, Rembeza, E, Newman, J, Kupinska, K, Diaz-saez, L, Kennedy, E, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.Show

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Primary Citation of related structures

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