6DN0 image
Deposition Date 2018-06-05
Release Date 2019-06-12
Last Version Date 2024-10-23
Entry Detail
PDB ID:
6DN0
Keywords:
IMMUNE SYSTEM
Title:
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.00 Å
R-Value Free:
0.23
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 31 2 1
6DN0 validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Human Variable Heavy Chain of
Chain IDs:A, C
Chain Length:136
Number of Molecules:2
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Human Variable Light Chain of
Chain IDs:B, D
Chain Length:106
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
FMT
Primary Citation
Retrofitting antibodies with stabilizing mutations
To be published ? ? ? (?)
Primary Citation of related structures
6DN0
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