6ARE image
Deposition Date 2017-08-22
Release Date 2018-05-30
Last Version Date 2025-04-02
Entry Detail
PDB ID:
6ARE
Keywords:
TRANSFERASE
Title:
Aspergillus fumigatus Cytosolic Thiolase in complex with two tetrahedral reaction intermediates and ammonium ions
Biological Source:
Source Organism(s):
Aspergillus fumigatus Af293 (Taxon ID: 330879)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.75 Å
R-Value Free:
0.23
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 1 21 1
6ARE validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Acetyl-CoA acetyltransferase,
Gene (Uniprot):erg10B
Mutagens:C92SCY
Chain IDs:A, B
Chain Length:399
Number of Molecules:2
Biological Source:Aspergillus fumigatus Af293
UniProt ID:Q4WCL5 Pfam ID:PF00108, PF02803 EC:2.3.1.9
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Acetyl-CoA acetyltransferase
Gene (Uniprot):erg10B
Chain IDs:C, D
Chain Length:399
Number of Molecules:2
Biological Source:Aspergillus fumigatus Af293
UniProt ID:Q4WCL5 Pfam ID:PF00108, PF02803 EC:2.3.1.9
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SCY A CYS modified residue
Ligand Molecules
ACO
ACT
CL
COA
NH4
Primary Citation
Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations
Acs Catalysis 8(3) 1973 1989 (2018)
DOI: 10.1021/acscatal.7b02873
Primary Citation of related structures
6AQP
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