ISDA: 5YD6

Deposition Date 2017-09-11

Release Date 2019-03-27

Last Version Date 2024-11-20

Entry Detail

PDB ID:

5YD6

Keywords:

TRANSCRIPTION

Title:

Crystal structure of PG-bound Nurr1-LBD

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.34 Å

R-Value Free:

0.26

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear receptor subfamily 4
Gene (Uniprot):NR4A2
Chain IDs:A, B, C, D
Chain Length:271
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P43354 Pfam ID:PF00104

Ligand Molecules

8SU

Primary Citation

Structure of Nurr1 bound to cyclopentenone prostaglandin A2 and its mechanism of action in ameliorating dopaminergic neurodegeneration in Drosophila

Rajan, S, Toh, H.T, Lim, K.H, Yoon, H.S.Show

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Primary Citation of related structures

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