5OL3 image
Deposition Date 2017-07-26
Release Date 2018-08-29
Last Version Date 2024-10-23
Entry Detail
PDB ID:
5OL3
Keywords:
TRANSFERASE
Title:
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp013 and RKp117
Biological Source:
Source Organism(s):
Cricetulus griseus (Taxon ID: 10029)
Expression System(s):
Escherichia coli 'bl21-gold(de3)plyss ag'
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.58 Å
R-Value Free:
0.19
R-Value Work:
0.15
R-Value Observed:
0.15
Space Group:
P 21 21 21
5OL3 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:cAMP-dependent protein kinase
Gene (Uniprot):PRKACA
Chain IDs:A
Chain Length:353
Number of Molecules:1
Biological Source:Cricetulus griseus
UniProt ID:P25321 Pfam ID:PF00069 EC:2.7.11.11
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:cAMP-dependent protein kinase
Chain IDs:B (auth: D)
Chain Length:18
Number of Molecules:1
Biological Source:Cricetulus griseus
UniProt ID:G3HK48
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SEP A SER modified residue
TPO A THR modified residue
Ligand Molecules
9LQ
CL
MPD
Primary Citation
Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage
Acs Omega ? ? ? (2019)
DOI: 10.1021/acsomega.8b02364
Primary Citation of related structures
5OL3
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