ISDA: 4UA4

Deposition Date 2014-08-08

Release Date 2014-09-17

Last Version Date 2023-12-20

Entry Detail

PDB ID:

4UA4

Keywords:

HYDROLASE

Title:

Structure of the VIM-2 Metallo-beta-Lactamase in Complex with a Bisthiazolidine Inhibitor

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.25 Å

R-Value Free:

0.16

R-Value Work:

0.14

R-Value Observed:

0.14

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-lactamase class B VIM-2
Gene (Uniprot):blaVIM-2
Chain IDs:A, B
Chain Length:242
Number of Molecules:2
Biological Source:Pseudomonas aeruginosa

UniProt ID:Q9K2N0 Pfam ID:PF00753 EC:3.5.2.6

Ligand Molecules

3C7

GOL

Primary Citation

Structure of the VIM-2 Metallo-beta-Lactamase in Complex with a Bisthiazolidine Inhibitor

Spencer, J.Show

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