4Q33 image
Deposition Date 2014-04-10
Release Date 2014-07-09
Last Version Date 2026-03-25
Entry Detail
PDB ID:
4Q33
Keywords:
Title:
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.89 Å
R-Value Free:
0.24
R-Value Work:
0.18
R-Value Observed:
0.18
Space Group:
P 1
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Inosine-5'-monophosphate dehy
Chain IDs:A, B, C, D, E, F, G, H
Chain Length:363
Number of Molecules:8
Biological Source:Clostridium perfringens
Primary Citation
A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity.
J. Biol. Chem. 290 5893 5911 (2015)
PMID: 25572472 DOI: 10.1074/jbc.M114.619767
Primary Citation of related structures
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